The GSV courses from the groin to the ankle on the inner aspect of the leg. The GSV is responsible for most visible bulging veins in the thigh and inner aspect of the calf. All veins have valves, and if the valve does not work right, then bulging varicosities occur through the branches of the GSV.
Venous reflux occurs when the valves that usually keep blood flowing out of your legs become diseased and no longer function as one-way valves. The blood refluxes back into your legs and is basically going the wrong way. The blood is being pushed back into the leg, instead of moving towards the heart for proper oxygenation. -- Also called: venous reflux
This is a thin tissue in the lumen of the vein itself. When working properly, the valve prevents blood from leaking back down the vein the wrong way. Valves may not work right due to hereditary or previous clots.